In the early phases of drug development, experimental in-vitro and in-vivo assessments of the drug candidate's ADMET (adsorption, distribution, metabolism, elimination, and toxicity) properties are a part of modern drug design and testing. Only a small portion of the suggested medicine candidates are approved by the government and are sold on the market. Most medication failures seen in the pharmaceutical industry are caused by undesirable pharmacokinetic features, poor bioavailability and efficiency, adverse side effects, poor solubility, and toxicity issues. In the hopes that the free exchange of scientific ideas and discoveries captured in this book would lead to improved pharmaceutical goods, authors from around the world have contributed information illuminating pharmaceutical problems, regulatory policies, and clinical properties in their various nations.
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- SKU: 9781632423511
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